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Effect of calcium silicate-based sealer to bone tissue of mandible of rats

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ÅÂÁö¼±, À¯±â¿¬, ±èÁø¿ì, Á¶°æ¸ð, ÀÌÀ±, ¹Ú¼¼Èñ,
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ÅÂÁö¼± ( Tae Jee-Seon ) - 
À¯±â¿¬ ( Yoo Ki-Yeon ) - 
±èÁø¿ì ( Kim Jin-Woo ) - 
Á¶°æ¸ð ( Cho Kyung-Mo ) - 
ÀÌÀ± ( Lee Yoon ) - 
¹Ú¼¼Èñ ( Park Se-Hee  ) - 

Abstract

"¸ñÀû: ¼¼ °¡Áö Ä®½· ½Ç¸®ÄÉÀÌÆ® °è¿­ ½Ç·¯°¡ ÈòÁã ÇϾǰñ Á¶Á÷¿¡ ¹ÌÄ¡´Â ¿µÇâÀ» Á¶Á÷ÇÐÀûÀ¸·Î Æò°¡ÇÏ°íÀÚ ÇÏ¿´´Ù.

¿¬±¸ Àç·á ¹× ¹æ¹ý: ÈòÁãÀÇ ÇϾǰñ¿¡ ¿Íµ¿À» Çü¼ºÇÏ°í Áï½Ã ¶Ç´Â 2ÁÖ ÈÄ Èñ»ýÇÑ ±º, ¿Íµ¿¿¡ CeraSeal (CS), AH Plus Bioceramic (AHB), One-Fil (OF) ½Ç·¯¸¦ °¢°¢ ÁÖÀÔÇÏ¿© 2ÁÖ ÈÄ Èñ»ýÇÑ ±ºÀ¸·Î ¹«ÀÛÀ§ ¹èÁ¤ÇÏ¿´´Ù. ¸ðµç ±ºÀ» Á¶Á÷ ó¸®ÇÏ°í Çö¹Ì°æ ÇÏ¿¡¼­ ¿Íµ¿ ³»¿Ü Æò±Õ °ñ ¸éÀû ºÐÀ²(%)À» °è»êÇÏ°í ÆÄ°ñ¼¼Æ÷¸¦ °è¼öÇÏ¿´°í, °¢ ±ºÀÇ °á°ú¸¦ ºñ±³ÇÏ°í ÀÏ¿øºÐ»ê ºÐ¼® ¹× Tukey¡¯s test·Î Åë°è ºÐ¼®ÇÏ¿´´Ù.

°á°ú: ¿Íµ¿ Çü¼º 2ÁÖ ÈÄ Èñ»ýÇÑ ´ëÁ¶±º°ú AHB ½Ç·¯ ÁÖÀÔ 2ÁÖ ÈÄ Èñ»ýÇÑ ±º¿¡¼­ ¿Íµ¿ ³» °ñÁ¶Á÷ Çü¼º°ú ÆÄ°ñ¼¼Æ÷ÀÇ Á¸À縦 È®ÀÎÇÒ ¼ö ÀÖ¾ú°í, ´Ù¸¥ ±ºµé¿¡ ºñÇØ À¯ÀÇÇÏ°Ô ³ôÀº ¿Íµ¿ ³» °ñ ¸éÀû ºÐÀ²(%)À» º¸¿©ÁÖ¾ú´Ù. ´Ù¸¥ ±ºµé¿¡¼­´Â ¿Íµ¿ ³» ¾î¶°ÇÑ ¿°ÁõÀ̳ª À̹° ¹ÝÀÀÀÌ ³ªÅ¸³ªÁö ¾Ê°í ÆÄ°ñ¼¼Æ÷ ¶ÇÇÑ °üÂûµÇÁö ¾Ê¾Ò´Ù.

°á·Ð: ½ÇÇè¿¡ »ç¿ëµÈ Ä®½· ½Ç¸®ÄÉÀÌÆ® °è¿­ ½Ç·¯´Â ÈòÁã ÇϾǰñ¿¡ ÁÖÀÔÇÏ¿´À» ¶§ ¾çÈ£ÇÑ °ñÁ¶Á÷ ¹ÝÀÀÀ» º¸¿´°í, ƯÈ÷ AHB¿¡¼­ ´õ ³ôÀº ¿Íµ¿ ³» °ñÁ¶Á÷ Çü¼ºÀÌ °üÂûµÇ¾ú´Ù."

Purpose: To histologically evaluate the effects of three calcium silicate-based sealers on rat mandible tissue.

Materials and Methods: Rats were randomly divided as follows: A group that sacrificed immediately after cavity preparation, a group that sacrificed two weeks after cavity preparation, a group that sacrificed two weeks after CeraSeal (CS), AH Plus Bioceramic (AHB), or One-Fil (OF) sealer injection, respectively. After tissue processing for all groups, the bone tissue area (%) and the number of osteoclasts in and around the cavity were measured under a microscope. The results of each group were compared and statistical analysis was performed using one-way ANOVA and Tukey¡¯s test.

Results: The formation of bone tissue and the presence of osteoclasts in the cavity were observed in the group that sacrificed two weeks after cavity preparation and the group sacrificed two weeks after AHB sealer injection, and these groups showed significantly higher average bone tissue area (%) than the other groups. In the other groups, no inflammation or foreign body reaction occurred in the cavity, and no osteoclasts were observed.

Conclusion: All calcium silicatebased sealers used in this study showed a favorable bone tissue response when injected into the rat mandible. In particular, higher bone formation in the cavity was observed in AHB.

Å°¿öµå

°ñ Àç»ý; °ñ ¸éÀû ºÐÀ²; Ä®½· ½Ç¸®ÄÉÀÌÆ® °è¿­ ½Ç·¯; ÆÄ°ñ¼¼Æ÷
bone regeneration; bone tissue area; calcium silicate-based sealer; osteoclast

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